GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs3796352 | 1 | rs35163227 | chr3:53127876 | SFMBT1 | chr3:52938628-53080070:- | -0.45 | -4.06 | 5.92E-5 | Immune reponse to smallpox (secreted IL-2) |
| BLCA | cis | rs7224737 | 1 | rs35184688 | chr17:40272406 | DHX58 | chr17:40253422-40264751:- | -0.25 | -4.59 | 5.98E-6 | Fibrinogen levels |
| BLCA | cis | rs9475752 | 1 | rs35202312 | chr6:56788937 | BEND6 | chr6:56819773-56892138:+ | -0.29 | -4.16 | 3.9E-5 | Menarche (age at onset) |
| BLCA | cis | rs2243480 | 1 | rs35283677 | chr7:65359233 | CCT6P1 | chr7:65216092-65228661:+ | 0.33 | 4.45 | 1.11E-5 | Diabetic kidney disease |
| BLCA | cis | rs950169 | 1 | rs35297609 | chr15:84772896 | LOC388152 | chr15:84867600-84898920:- | -0.27 | -4.65 | 4.65E-6 | Schizophrenia |
| BLCA | cis | rs12908161 | 1 | rs35316992 | chr15:85248133 | LOC388152 | chr15:84867600-84898920:- | -0.25 | -4.2 | 3.37E-5 | Schizophrenia |
| BLCA | cis | rs4776059 | 1 | rs35372377 | chr15:52882281 | ARPP19 | chr15:52839432-52861364:- | 0.22 | 4.14 | 4.36E-5 | Schizophrenia |
| BLCA | cis | rs1577917 | 1 | rs35385043 | chr6:86648546 | SNHG5 | chr6:86386726-86388451:- | -0.55 | -10.06 | 2.7E-21 | Response to antipsychotic treatment |
| BLCA | cis | rs2243480 | 1 | rs35391607 | chr7:65360829 | CCT6P1 | chr7:65216092-65228661:+ | 0.31 | 4.38 | 1.53E-5 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs35396113 | chr7:65495461 | CCT6P1 | chr7:65216092-65228661:+ | 0.31 | 4.39 | 1.48E-5 | Diabetic kidney disease |
| BLCA | cis | rs1577917 | 1 | rs35419329 | chr6:86702291 | SNHG5 | chr6:86386726-86388451:- | -0.52 | -9.26 | 1.43E-18 | Response to antipsychotic treatment |
| BLCA | cis | rs2243480 | 1 | rs35421653 | chr7:65363429 | CCT6P1 | chr7:65216092-65228661:+ | 0.33 | 4.45 | 1.11E-5 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs35432774 | chr7:65393019 | CCT6P1 | chr7:65216092-65228661:+ | 0.31 | 4.38 | 1.53E-5 | Diabetic kidney disease |
| BLCA | cis | rs9894429 | 1 | rs35435780 | chr17:79579602 | TSPAN10 | chr17:79609349-79615778:+ | 0.49 | 8.84 | 3.52E-17 | Eye color traits |
| BLCA | cis | rs6932590 | 1 | rs35454259 | chr6:27254475 | BTN3A2 | chr6:26365398-26378546:+ | -0.29 | -4.71 | 3.51E-6 | Schizophrenia |